In the first week of July 2020, Dynamo St. Petersburg unexpectedly announced that they would be withdrawing from the league immediately, due to insufficient funding.
[1] Seven Dynamo players were then signed by SK Gorny St. Petersburg, but that club soon ran into financial difficulties as well, due in large part to being dropped by their main sponsor.
Playing out of Podmoskovie Ice Palace in Voskresensk, Moscow Oblast, 7.62's roster was filed entirely by players 18 and under, several of whom were members of the Russian national junior team.
SKIF Nizhny Novgorod improved from sixth place in the 2019–20 regular season to claim third place in 2020–21 and were the only team to pose a legitimate threat to Agidel's position in second, ultimately tying Agidel with 60 points and winning more games overall but prevented from higher ranking by an excess of overtime wins in relation to relegation victories.
Biryusa Krasnoyarsk claimed fourth place in a repeat of the previous season and trailing the other top ranked teams, with 47 points and a 15-9-4 record.
Agidel Ufa winger and alternate captain Olga Sosina topped the league in assists, notching 32 in 27 games and ranking third in scoring with 50 points (18+32).
Megan Bozek of the KRS Vanke Rays was the highest scoring defenceman, earning 36 points (13+23) and ranking eighth overall.
[15] On 22 March, the league announced that the finals would be postponed until after the 2021 IIHF Women's World Championship Top Division tournament, which had been rescheduled to be held from 6–16 May in Nova Scotia, Canada.
In contrast, Agidel Ufa added only one player – 15 year old Maria Mikaelyan – and participated in the final with a nearly identical roster to the 2020–21 season.