[17] Zamalek earned a place in the match after defeating RS Berkane in the 2019 CAF Confederation Cup Final 5–3 on penalties after being tied 1–1 on aggregate.

All of their previous six encounters were in the Champions League, including the 1994 final which was won by Espérance de Tunis where they grabbed their only victory against Zamalek in the second leg.

Nine days before the match, the 2019–20 CAF Champions League knockout stage draw was held at the Hilton Pyramids Golf in Cairo, Egypt and resulted in Zamalek being drawn against Espérance de Tunis; meaning that both teams would face each other three times in three weeks.

[19] Prior to their league game against US Tataouine, Espérance de Tunis announced that defender Abdelkader Bedrane has suffered from a torn ligament and would be sidelined for at least three weeks, missing the CAF Super Cup as a result.

[20] Zamalek captain Mahmoud Shikabala suffered from an injury during training with the club in January 2020 and was still in the recovery stage.