The 23rd running of the women's Flèche wallonne was originally planned on 22 April 2020, but was rescheduled to 30 September 2020 due to the COVID-19 pandemic.

The route featured seven categorized climbs, including two ascents of the Mur de Huy.

The finish line was on the top of the final ascent of the Mur.

[2] For the first time in its 23-year history, the women's race was broadcast live.

The race was won for the sixth consecutive time by Dutch rider Anna van der Breggen.