The Red Raiders played their home games on the university's campus in Lubbock, Texas at Jones AT&T Stadium, and competed as members of the Big 12 Conference.

[2] References:[3] Listed in the order that they were released The Big 12 media days were held on July 21–22, 2020 in a virtual format due to the COVID-19 pandemic.

[8] Texas Tech had games scheduled against Alabama State, Arizona, and UTEP, but were canceled due to the COVID-19 pandemic.

Texas Tech received the opening kickoff and quickly went downfield with Alan Bowman finding Erik Ezukanma for a 7-yard touchdown pass with 13:22 left in the first quarter.

On their next drive, the Huskies made it to the Texas Tech 1-yard line, but a pass by wide receiver Jerreth Sterns was intercepted by Zech McPhearson.

The next play was quickly blown dead due to an illegal holding penalty against Houston Baptist, moving the team back 10 yards.

The quarter ended with a 14-yard pass from Zappe to Ben Ratzlaff, putting Houston Baptist in Texas Tech territory.

The Red Raiders quickly went down field, capping the drive with an 18-yard touchdown pass from Bowman to KeSean Carter to extend the lead to 35–20.

The fifteen point lead would be short lived, as Houston Baptist responded on the first play the following drive, with Zappe throwing a 75-yard touchdown pass to Sterns.

Texas Tech had a chance to out the game away on its following drive, but turned the ball over on downs at the Houston Baptist 4-yard line with 5:25 left in regulation.

The Huskies found the end zone on the next play with Zappe throwing a 6-yard pass to Sterns to make it 33–35 with 3:23 left in regulation.

After being down 21–31 at halftime, the Red Raiders stormed back in the 3rd quarter, scoring 21 points while only giving up 7, to lead 42–38 heading into the 4th.

Texas recovered an onside kick on the ensuing kickoff and scored another touchdown on the drive to trail 54–56 and made the two-point conversion to tie the game 56–56 with 0:40 left in regulation.

The Red Raiders took an early 3–0 lead with a 48-yard field goal Jonathan Garibay, who was making his first collegiate start after struggles from incumbent starter Trey Wolff.