It was the second of three BWF tournaments taking place in Thailand in January 2021 following a break caused by the COVID-19 pandemic.

Participation in both Thailand Opens was mandatory to qualify for the 2020 BWF World Tour Finals.

The Chinese team withdrew from all three tournaments after failing to get permission to travel to Thailand; affected players include Chen Qingchen and Jia Yifan (women's doubles), and Zheng Siwei and Huang Yaqiong (mixed doubles).

[3] In addition, the Japanese team has withdrawn from the tournaments following the positive COVID-19 diagnosis of Kento Momota (men's singles).

[4] Following Kevin Sanjaya Sukamuljo's positive COVID-19 diagnosis, he and Marcus Fernaldi Gideon (men's doubles) withdrew from the tournaments.