Vanderbilt competed in the Eastern Division of the Southeastern Conference (SEC).

Coach Tim Corbin led the Commodores in his 18th season with the program.

[2] In addition, the Commodores were highly ranked in preseason and subsequent polls, beginning at #1 according to the preseason ESPN/USA Today Coaches poll and closing at #7 on March 16, the final ranking.

On March 12, Vanderbilt University declared that all spring sports were suspended for the remainder of the season.

[3] On March 30, the NCAA canceled the upcoming College World Series,[4] but announced that senior spring athletes would have the opportunity to return to school for the 2021 spring season if they wished.