[1][2][3] On 13 September, two clubs Široki and Zlatibor were awarded with wildcards fulfilling the remaining spots.

The labels in the parentheses show how each team qualified for the place of its starting round: Note CRO: In July 2021, a Croatian team Adria Oil Škrljevo withdrew its bid to join the Alpe Adria Cup for the 2021–22 season.

[8] A Croatian team Gorica has been applied for the Alpe Adria Cup in the upcoming season, also.

The hosts are Zlatibor in Serbia, Osijek in Croatia, and Banja Luka, Sarajevo, and Široki Brijeg in Bosnia and Herzegovina.

[20][24] Originally scheduled for 17–23 January 2022, the Banja Luka Tournament was rescheduled to 6–12 February due to COVID-19 outbreaks.