The regular season ended on February 26, 2022, followed by the 2022 ASUN men's basketball tournament held March 1–8, 2022.

Due to the offseason additions of Central Arkansas, Eastern Kentucky, and Jacksonville State, the ASUN changed the conference play format.

The East includes Florida Gulf Coast, Jacksonville, Kennesaw State, Liberty, North Florida and Stetson, while the West features Bellarmine, Central Arkansas, Eastern Kentucky, Jacksonville State, Lipscomb and North Alabama.

Notes: The ASUN preseason men's basketball poll was released on October 20, 2021.

[2] First Place Votes in Parentheses First Place Votes in Parentheses *unanimous selection The 2022 ASUN Tournament was held at the higher seeded team's home court from March 1, 2022 to March 8, 2022.