[6] On 27 June, Monaco announced the loan signing of Alexander Nübel from Bayern Munich, until the end of the 2022–23 season.

[10] On 20 July, youngsters Boris Popovic and Edgaras Utkus joined Cercle Brugge on loan for the season.

[15] On 11 August, Monaco announced that Gabriel Pereira had left the club to return to Brazil and sign with Athletico Paranaense.

[19] On 25 August, Pietro Pellegri joined A.C. Milan on loan for the season, with the option to make the move permanent.

[20] On 28 August, Antonio Barreca left Monaco to join Lecce on a season-long loan deal.

[23] Also on 31 August, Keita Baldé left Monaco to sign permanently for Cagliari, whilst Julien Serrano was also released by the club.