The 2021–22 America East Conference men's basketball season started non-conference play on November 9, 2021, and began conference play on January 2, 2022.

Binghamton named Levell Sanders interim head coach after Tommy Dempsey's contract was not renewed.

UMBC hired Jim Ferry after Ryan Odom left to become the head coach at Utah State.

Notes: *Interim Head Coach for 2021-22 Season The Preseason America East Conference men's basketball polls was released on October 21, 2021.

The top 8 teams from the America East qualify for the conference tournament.