The 2021–22 Andebol 1 (known as the Campeonato Placard Andebol 1) was the 70th season of the Andebol 1, Portuguese premier handball league.
It ram from 18 September 2021 to 4 June 2022.
[1] Porto won their twenty-third title.
[2] The following 16 clubs compete in the Portuguese League during the 2021–22 season:
The first place promoted to Andebol 1 and the last two relegated to Santo Tirso.