The 2021–22 Appalachian State Mountaineers men's basketball team represented Appalachian State University in the 2021–22 NCAA Division I men's basketball season.

The Mountaineers, led by third-year head coach Dustin Kerns, played their home games at the Holmes Center in Boone, North Carolina as members in the Sun Belt Conference.

In a season limited due to the ongoing COVID-19 pandemic, the Mountaineers finished the 2020–21 season 17–12, 7–8 in Sun Belt play to finish in fourth place in the West Division.

In the Sun Belt tournament, they defeated Little Rock in the first round,[2] Texas State in the quarterfinals,[3] and Coastal Carolina in the semifinals to advance to the championship game.

[4] In the championship game, they defeated Georgia State, sending the Mountaineers to their third ever NCAA tournament appearance, and their first since 2000.