The 2021–22 Austin Peay Governors men's basketball team represented Austin Peay State University in the 2021–22 NCAA Division I men's basketball season.

The Governors, led by first-year head coach Nate James, played their home games at the Winfield Dunn Center in Clarksville, Tennessee as members of the Ohio Valley Conference (OVC).

6 seed in the OVC tournament, they lost to Tennessee Tech in the first round.

After the season, the Governors left the OVC, their home since 1962, to join the ASUN Conference.

[6] In the OVC tournament, they lost to Eastern Kentucky in the first round.