[1] Dender EH became champions on 25 May 2022 after winning their final match of the Promotion play-offs at home to Dessel, while their only remaining opponent RFC Liège, lost away to Knokke.
Going into the playoffs, only Dender EH and RFC Liège had applied for a Belgian professional football license, meaning that only those two teams were eligible for promotion.
With just one matchday to go and RFC Liège two points ahead of Dender EH, a ruling was made on an earlier complaint by the Belgian FA that RFC Liège had not put sufficient U21 players on the match sheet during their regular season match against Dender EH.
The result of that match was changed from a 3–0 home win to a 0–5 forfeit loss, causing the starting points of RFC Liège to be lowered by one to 24 and those of Dender EH increased by two to 25.
RFC Liège appealed this decision, but then lost the final match (while Dender EH won) before a ruling was made, meaning the outcome didn't matter.