The season started on 27 November 2021 in Östersund, Sweden and ended on 20 March 2022 in Oslo Holmenkollen, Norway.

[1] Norwegians Johannes Thingnes Bø and Tiril Eckhoff were the defending overall champions from the 2020–21 season.

For the first time in the history of the Biathlon World Cup, the competition will be held in Estonia, specifically in Otepää.

Previously, the Ukrainian national team announced the withdrawal from the biathlon competition by the end of the season.

The table shows the number of points won in the 2021–22 Biathlon World Cup for men and women.