The season was the first since 2009–10 without Łukasz Piszczek, who departed to LKS Goczałkowice-Zdrój.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Win Draw Loss Fixtures Source: Soccerway Source: DFB The league fixtures were announced on 25 June 2021.

The knockout round play-offs draw was held on 13 December 2021.