The 2021–22 Cape Town Tigers season is the 2nd season in the existence of the Cape Town Tigers.
Cape Town began its qualification October 21, 2021 and started its debut season in the BAL on April 10, 2022.
The Tigers were led by head coach Relton Booysen.
Note: Flags indicate national team eligibility at FIBA-sanctioned events.
Players may hold other non-FIBA nationalities not displayed.