The draw for the Final Rounds was held on 22 December 2021, 15:00 at AFA Futsal Stadium in Ezeiza.
Champions of AFA tournaments playing in Argentine Primera División were allocated to Group A.
The matches were drawn from the respective confronts: A vs. C; B vs. D. Some combinations were avoided for security reasons.
The round was played between 23 February and 1 June 2022, in a single knock-out match format.
The round was played between 8 June and 4 August 2022, in a single knock-out match format.
The round was played between August 9 and September 15, in a single knock-out match format.