The 2021–22 Eastern Washington Eagles men's basketball team represented Eastern Washington University in the Big Sky Conference during the 2021–22 NCAA Division I men's basketball season.

The Eagles, led by first-year head coach David Riley, played their home games on campus at Reese Court in Cheney, Washington.

The Eagles finished the 2020–21 season 13–7 overall (12–3, Big Sky, 2nd) and was seeded second in the conference tournament, which they won.

Seeded fourteenth in the West regional of the NCAA tournament, they met twelfth-ranked Kansas in the round of 64.

The Eagles scored the first nine points and led by eight at the half, but were overcome by the Jayhawks in the last ten minutes and lost by nine points; their season ended with an overall record of 16–8 (.667).