The 2021–22 season was the 95th season in the existence of FC Dynamo Kyiv and the club's 31st consecutive season in the top flight of Ukrainian football.

In addition to the domestic league, Dynamo Kyiv participated in this season's editions of the Ukrainian Cup, the Ukrainian Super Cup, and the UEFA Champions League.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Players may hold more than one non-FIFA nationality.

Win Draw Loss Source: Soccerway The draw for the group stage was held on 26 August 2021.