The 2021–22 FC Ingolstadt 04 season was the 18th edition of FC Ingolstadt 04's existence, the club's first season return in the 2.

Bundesliga, the second tier of German football, following their promotion from the 3.

The club contested in the DFB-Pokal.

Liga, level on points with second-placed Hansa Rostock and losing out on automatic promotion as a result of their inferior goal difference, although they did qualify for the play-offs.

[1] They won the promotion play-offs 4–3 on aggregate against VfL Osnabrück and were promoted as a result.