In addition to the domestic league, FC Nizhny Novgorod participated in this season's editions of the Russian Cup, where they were eliminated in round of sixteen.

[1] Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Anisimov & Sinitsyn both played in Nizhny Novgorod 1-0 victory over Dynamo Barnaul on 22 September 2021