[2] On 10 June, Rostov announced the permanent signing of Ali Sowe from CSKA Sofia on a contract until 2025 following a successful loan spell.

[11][12] On 29 August, Mathias Normann joined Norwich City on a season-long loan deal, with the option to make the move permanent.

[13] On 31 August, David Toshevski joined Górnik Zabrze on a season-long loan deal, with the option to make the move permanent.

[20] Two days later, 25 December, Rostov announced that goalkeeper Maksim Rudakov had joined Honka on loan for the 2022 Veikkausliiga season.

[22] On 29 December, Rostov announced the signing of Aleksandr Selyava from Dinamo Minsk on a contract until the end of the season with the option of an extension.

[26] On 24 February, Rostov's home match against Krylia Sovetov was postponed due to the local airport being shut by the Federal Air Transport Agency in relation to the Russian invasion of Ukraine.

[30] Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.