2021–22 FUFA Big League

[2] Lira-based Blacks Power won the Big League title after defeating Luweero United 2–1 on the last match day.

Kataka led the league entering the final match day but not even secure promotion.

Kyetume defeated Kataka 3–2 on the final match day to move above them in the table.

Proline were also relegated after having a bye in the final round, which allowed Ndejje University to move above them with a 5–0 win over Kitara.

[3] Kyetume was later denied promotion for failing to meet licensing requirements, and was relegated to the third division.