Fortuna Düsseldorf finished the 2020–21 season in 5th place, 8 points below the automatic promotion places and 6 points below the promotion play-off place.
[1] Manager Uwe Rösler's contract was not renewed at the end of the previous season.
[2] Christian Preußer was appointed as manager in May 2021.
[3] Preußer was sacked as manager on 8 February 2022, and replaced by Daniel Thioune.
[4] Düsseldorf finished the season in 10th.