The 2021–22 Ghana Premier League was the 66th season of the top professional association football league in Ghana[1] which began on 29 October 2021 and concluded on 19 June 2022.
[3] Asante Kotoko won the league for a record-extending 25th time and the first since 2014 after a 1–1 draw against Ashanti Gold[4] and were handed the trophy on the season's final day after a 3-0 triumph over relegated Elmina Sharks.
[7] They replaced Ebusua Dwarfs, Liberty Professionals and Inter Allies.
On July 17 the GFA annound that there will be a play-off between the three second-placed clubs in the Division One Leagues.
The three 2nd placed clubs, Tamale City FC, Mysterious Ebusua Dwarfs FC and Liberty Professionals will play in a three-way League to determine the replacement for AshantiGold SC.