The 2021–22 Greek A Division is the 33rd season of the women's football top-level league in Greece.
The separation of the teams into these groups will take place based on geographical criteria.
In the 1st phase, the teams of each group will compete in two rounds.
In the 2nd phase, a play-off round will be held to determine the champion.
No matches will be held between the teams that competed in the same group in Phase A.