It started on 8 October 2021 with the first round of the regular season and ended on 19 June 2022 with the Final Four.
For this season, the league was back to 18 teams and brought back the single group with a single group phase in which the top team of the regular season promoted directly to Liga ACB.
[2][3] A total of 18 teams contested the league, including 14 sides from the 2020–21 season, two relegated from the 2020–21 ACB and two promoted from the 2020–21 LEB Plata.
On July 5, 2021, Real Murcia resigned to play in the league due to lack of financial support.
Source: FEB The Copa Princesa de Asturias was played by the two first qualified teams after the end of the first half of the season (round 17).