The 2021–22 LNH Division 1 (known as the Liqui Moly StarLigue for sponsorship reasons) was the 70th season of the LNH Division 1, French premier handball league and the 45th season consisting of only one league.
It ram from 10 September 2021 to 8 June 2022.
[1] Paris Saint-Germain won their ninth title.
[2] The following 16 clubs compete in the LNH Division 1 during the 2021–22 season: The awards were announced on 10 June 2022.
[4] The all-star team was announced on 10 June 2022.