Seven clubs competed with a total of 16 teams for one spot in the second qualifying round of the 2022–23 UEFA Europa Conference League.

FC Vaduz were the defending champions.

The first round involved all except the eight highest-placed teams.

[2] The quarter-finals involved the four teams who won in the second round, as well as the top four highest placed teams (FC Vaduz, FC Balzers, USV Eschen/Mauren and FC Ruggell).

[3] The semi-finals involved the four teams who won in the quarter-final round.