[1][2] The reigning champions entering the season where Complutense Cisneros who claimed their 1st league title after winning the 2020-21 final against Majadahonda.

[3] Eight teams competed in the league – the top seven teams from the previous season and Sant Cugat who were promoted as champions of the 2020–21 Honor Division B.

[4] They replaced Les Abelles who were relegated after just one season in the top flight.

Second to last plays a relegation playoff against Honor Division B runner-up.

The team finishing in 7th place faces the runner-up of the Honor Division B, with the winner of this match playing in the 2022–23 Liga Iberdrola and the loser in the 2022–23 Honor Division B.