In addition to the domestic league, Lille participated in this season's editions of the Coupe de France, the Trophée des Champions, and the UEFA Champions League.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Win Draw Loss Fixtures Source: Soccerway Source: Ligue 1 The league fixtures were announced on 25 June 2021.