The 2021–22 Louisiana Ragin' Cajuns men's basketball team represented the University of Louisiana at Lafayette during the 2021–22 NCAA Division I men's basketball season.

The Ragin' Cajuns, led by twelfth-year head coach Bob Marlin, played their home games at the Cajundome as members of the Sun Belt Conference.

The Ragin' Cajuns finished the 2020–21 season 17–9,[1] 10–7 in Sun Belt play to finish second in the conference's Western Division.

[2] The Cajuns proceeded to the Sun Belt Conference Men's Basketball Tournament.

After receiving a first-round bye, they ultimately lost to the Georgia State Panthers.