The 2021–22 Marquette Golden Eagles men's basketball team represented Marquette University during the 2021–22 NCAA Division I men's basketball season.

The team were led by first-year head coach Shaka Smart and played their home games at Fiserv Forum in Milwaukee, Wisconsin as a member of the Big East Conference.

5 seed, they lost in the quarterfinals of the Big East tournament to Creighton.

9 seed in the East Region, where they lost in the First Round to North Carolina.

[1] On March 19, 2021, the school fired head coach Steve Wojciechowski.