The 2021–22 Marsh One-Day Cup was the 53rd season of the official List A domestic cricket competition played in Australia.

[2] On 8 September 2021, Cricket Australia announced that the aforementioned schedule had been scrapped due to ongoing lockdowns in Sydney and Melbourne and subsequent border closures.

[5] On 20 October 2021, Cricket Australia confirmed the next set of fixtures, following the border openings in Sydney and Melbourne.

[7] After a shortened tournament due to the COVID-19 pandemic, Western Australia and New South Wales had progressed to the final.

[8] In the final, Western Australia beat New South Wales by 18 runs to win their 15th one-day title.