They represented the University of Michigan in the 2021–22 NCAA Division I men's ice hockey season.

They were coached by Mel Pearson, in his fifth year, and played their home games at Yost Ice Arena.

The Wolverines won the 2022 Big Ten men's ice hockey tournament and received an automatic bid to the 2022 NCAA Tournament, where they reached their NCAA record 26th Frozen Four and were eliminated in the semifinals by eventual national champion Denver.

They received an at-large bid to the 2021 NCAA Division I men's ice hockey tournament, however, they were removed from the tournament due to positive COVID-19 test results within the program.

[24] Michigan's 2021–22 roster had an NCAA record seven first round draft picks.