The 2021–22 NC State Wolfpack men's basketball team represented North Carolina State University during the 2021–22 NCAA Division I men's basketball season.

The Wolfpack were led by fifth-year head coach Kevin Keatts and played their home games at PNC Arena in Raleigh, North Carolina as members of the Atlantic Coast Conference (ACC).

As the fifteenth seed in the ACC tournament, they lost to Clemson in the first round.

[1] They received an at-large bid to the National Invitation Tournament as the third seed in the Colorado State bracket.

[2] The Wolfpack defeated Davidson in the first round[3] before losing to Colorado State in the quarterfinals.