The 2021–22 NK Istra 1961 season was the club's 61st season in existence and the 13th consecutive season in the top flight of Croatian football.
Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.
Players may hold more than one non-FIFA nationality.
Source: Glasilo Hrvatskog nogometnog saveza Source: Glasilo Hrvatskog nogometnog saveza Total spending: 0 € Total income: 0 € Total expenditure: 0 € Last updated: 21 May 2022 Source: Soccerway Last updated: 21 May 2022.
Source: Prva HNL Source: Croatian Football Federation Source: Croatian Football Federation[50] Updated 21 May 2022 Source: Competitive matches Source: Competitive matches