EV Zug defended their title after beating ZSC Lions in the finals 4–3.
13 teams participated in the season as HC Ajoie was promoted to the National League after winning 2020–21 Swiss League.
The following shows the top ten players who led the league in points, at the conclusion of the regular season.
[1] If two or more skaters are tied (i.e. same number of points, goals and played games), all of the tied skaters are shown.
The following shows the top ten goaltenders who led the league in goals against average, provided that they have played at least 40% of their team's minutes, at the conclusion of the regular season.