The Highlanders are all set rope in Spanish midfielder Hernan Santana and Sehnaj Singh and have extended Khassa Camara’s contract, as reported earlier by Khel Now.

The club has also signed Joe Zoherliana, Jestin George, and Mohammed Irshad under the guidance of Khalid Jamil who is set to continue as head coach.

On 27 October 2021, NorthEast United are completed the signing of Australian defender Patrick Flottmann from Sydney FC on a free transfer.

The Highlanders first signed South Korean defender Ahn Byung-keon, but couldn’t register him due to some issues.

[4] On 7 November 2021, NorthEast United FC confirmed the signing of Pragyan Medhi on its social media and various other platforms for the upcoming season.

[8][9] On 20 November 2021, NorthEast United lost 2–4 against Bengaluru FC in their first Indian Super League match of the season.

[11] On 27 November 2021, NorthEast United announced Health Vit as their Official Nutrition Partner for the upcoming season.

[12] On 29 November 2021, NorthEast United lost 1–2 against Chennaiyin FC in their third Indian Super League match of the season.

[20] On 29 December 2021, NorthEast United assistant manager Alison Kharsyntiew left the club due to family issue.

[23] On 13 January 2022, Khelnow confirmed that NorthEast United signed Senegalese defender Zakaria Diallo for the rest of the season.

[24] NorthEast United also terminate their contract with Khassa Camara due to his engagements with AFCON that rules him out for a majority of matches in the second phase of Indian Super League.

[27] On 21 January 2022, NorthEast United confirmed the signing of Marco Sahanek on its social media and various other platforms for the rest of the season.

On 28 February, NorthEast United drew 1–1 with East Bengal in their last match of the Indian Super League season.