2021–22 PFC Ludogorets Razgrad season

[7] On 30 June, Vladislav Stoyanov, Cosmin Moți and Svetoslav Dyakov all left Ludogorets after their contracts ended.

[14] On 28 December, goalkeeper Kristijan Kahlina was sold to Major League Soccer club Charlotte FC.

[18] On 31 January, Ludogorets announced that Elvis Manu had left the club by mutual consent, and that they had signed Simon Sluga from Luton Town.

[21] [22] The following day, 3 February, Josué Sá joined Maccabi Tel Aviv on loan for the rest of the season.

[24] Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.