It began on 4 August 2021 with the first matches of the preliminary round and ended with the final on 2 May 2022 at Stadion Narodowy.
[2] Raków successfully defended their title by defeating Lech Poznań 3–1 in the final.
[3] The PZPN Board of Directors determined the size of the prizes.
Participating in this round were the 10 lowest ranked teams from 2020–21 II liga (which finished 2020–21 season on positions 10-19).
[6] The draw for this round was conducted in the headquarter of PZPN on 12 August 2021.