The Spiders, led by third-year head coach Aaron Roussell, played their home games at the Robins Center and were members of the Atlantic 10 Conference.

3 seed Saint Louis in the quarterfinals, with both games requiring overtime.

[1][2] Roster Last update: May 12, 2022 Richmond's 2021–22 non-conference schedule featured 13 games, including a pair of games in the Cavalier Classic in Charlottesville, Virginia, and another pair in the FAU Pre-Christmas Tournament in Boca Raton, Florida.

In addition, Richmond hosted Massachusetts, Dayton, Davidson, Rhode Island and Fordham, while the Spiders traveled to George Washington, Saint Joseph's, George Mason, Saint Louis, and St.

9 seed Davidson in the second round of the A-10 women's tournament, falling by a score of 66–62.