Domestically, Benfica played in the Primeira Liga, were eliminated in the fifth round of Taça de Portugal, and reached the Taça da Liga final.

In Europe, Benfica reached the quarter-finals of the UEFA Champions League.

This was Benfica's second consecutive season and third year without any trophy won.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Source: [citation needed] The draw for the third qualifying round was held on 19 July 2021.