On 18 October 2021 club signed with Nihat Jaman Ucchash on free transfer from Arambagh KS.

On 22 October 2021 the club has confirmed signed Bangladesh Police FC midfielder Nazmul Islam Rasel on free transfer.

On 28 November 2021 Saif Sporting Club has started their 2021-22 football season by defeated 2–1 goals Bangladesh Army.

In second half 90+1 minutes Mohammedan SC defender Rajib Hossain goal level the scored.

On 25 minutes Nabib Newaj Jibon scored for Dhaka Abahani and with a goal finished first half.

Goals on 34 minutes Maraz Hosain and 38 Uzbekistan forward Asor Gafurov SSC end first half.

In the second half 81 minutes Chittagong Abahani Shakhawat Hossain Rony scored a goal but isn't enough to avoid lost the match.

In the second half 71 minutes Maraz Hossain made the scored 2–0 and Saif SC with 3 points qualified to Semi-finals.

[18] On 4 February Saif Sporting Club had their season's first home match against Bangladesh Police FC and won by 1–0 goal.

In the second half Sheikh Russel KC tried to extended the lead but Saif Sports Club also tried to equalized score but they won't able to do it.

In the second half in between 4 minutes a goal by Md Shahriar Emon Dhaka Mohammdan extended the lead 2–0.

Rest of the time of second half Saif Sporting Club didn't able to score any goal and Dhaka Mohammdan got three points.

[33] On 3 July Saif Sporting Club have won by 4–2 goals versus Dhaka Abahani at home ground.

[34] On 8 July Saif Sporting Club have drawn against Sheikh Jamal DC by 2–2 goals in the away game.

[37] On 31 July Saif Sporting Club have lost against Muktijoddha Sangsad KC by 2–3 goals at home ground.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.