The team played their home games at Chaifetz Arena as a member of the Atlantic 10 Conference.

They defeated La Salle and St. Bonaventure to advance to the semifinals of the A-10 tournament where they lost to Davidson.

They received an at-large bid to the National Invitation Tournament where they lost in the first round to Northern Iowa.

They received an at-large bid of the National Invitation Tournament where they lost to Mississippi State in the first round.

[1] In the preseason game against Rockhurst, Perkins suffered a torn anterior cruciate ligament (ACL) in his left knee and will miss the remainder of the 2021–22 season.