The 2021–22 San Diego State Aztecs men's basketball team represented San Diego State University during the 2021–22 NCAA Division I men's basketball season.

The Aztecs, led by fifth-year head coach Brian Dutcher, played their home games at Viejas Arena as members in the Mountain West Conference.

They received an at-large bid to the NCAA tournament as the No.

8 seed in the Midwest Region, where they lost in the first round to Creighton.

As a result, they received the conference's automatic bid to the NCAA tournament as the No.