The 2021–22 Seton Hall Pirates men's basketball team represented Seton Hall University in the 2021–22 NCAA Division I men's basketball season.

The Pirates played their home games at the Prudential Center in Newark, New Jersey and Walsh Gymnasium in South Orange, New Jersey as members of the Big East Conference.

They defeated Georgetown in the first round of the Big East tournament before losing in the quarterfinals to UConn.

[2] In a season limited due to the ongoing COVID-19 pandemic, the Pirates finished the 2020–21 season 14–13, 10–9 in Big East play to finish in a tie for fourth place.

5 seed in the Big East tournament, they defeated St. John's in the quarterfinals before losing to Georgetown in the semifinals.