The 2021–22 Swiss Challenge League (referred to as the Dieci Challenge League for sponsoring reasons) was the 19th season of the Swiss Challenge League, the second tier of competitive football in Switzerland, under its current name.
They were replaced by FC Vaduz, who was relegated after finishing last-placed in the 2020–21 Swiss Super League.
FC Chiasso was relegated after finishing in last place in the 2020–21 Swiss Challenge League and was replaced by Yverdon-Sport FC, who finished atop the 2020-21 Swiss Promotion League.
[7][8] The runner-up of the Challenge League hosted the first game.
[9] FC Schaffhausen was confirmed as the runner-up of the Challenge League on 21 May 2022.