Participating teams included the Kaohsiung Aquas, New Taipei CTBC DEA, Taichung Wagor Suns, Tainan TSG GhostHawks, TaiwanBeer HeroBears, and the Taoyuan Leopards.
Each team played against another six times, three at home and three on the road, respectively, led to 30 matches in total.
The regular season started on November 27, 2021 and ended on May 20, 2022.
[1][2][3] The 2021–22 season opening game, matched by the Kaohsiung Aquas and the TaiwanBeer HeroBears, was played at University of Taipei Tianmu Campus Gymnasium.
[4] MVP of the Month awards were only for local players.